Search Result : Detailed Informations

Allergen-Scientific Name Taxonomy Name Genbank Common Name Category
Ara h 1 Arachis hypogaea Peanut
IsoAllergen Source of Allergen Name
IsoAllergen
AOL

<Sequences>

DataSource UniProt Acc Motif

Original Reference

(gi number)

Allergen Description
P43237 ADFS_0006 1168390 Allergen Ara h 1, clone P17 , Allergen Ara h I , Allergen=Ara h 1
E5G076 ADFS_0006 312233063 Ara h 1 allergen
P43238 ADFS_0006 375332427 Allergen Ara h 1, clone P41B , Allergen Ara h I , Allergen=Ara h 1
P43238 ADFS_0006 347447588 Allergen Ara h 1, clone P41B , Allergen Ara h I , Allergen=Ara h 1

Structural Information

Domain Information


<Epitope Information (1)>

Pubmed 9593717
Uniprot Acc. P43237
Title Biochemical and structural analysis of the IgE binding sites on ara h1, an abundant and highly allergenic peanut protein.
Author Shin DS, Compadre CM, Maleki SJ, Kopper RA, Sampson H, Huang SK, Burks AW, Bannon GA.
Journal J Biol Chem. 1998 May 29;273(22):13753-9.
Method
No. Epitope Sequences Blast Search Start End Description Type
1 AKSSPYQKKT Epitope / Protein 25 34 When altered, amino acids shown in red lead to a decrease of IgE binding: AKSSPYQKKT
2 QEPDDLKQKA Epitope / Protein 48 57 When altered, amino acids shown in red lead to a decrease of IgE binding: QEPDDLKQKA
3 LEYDPRLVYD Epitope / Protein 65 74 When altered, amino acids shown in red lead to a decrease of IgE binding: LEYDPRLVYD Mutation: C71L
4 GERTRGRQPG Epitope / Protein 89 98 When altered, amino acids shown in red lead to a decrease of IgE binding: GERTRGRQPG
5 PGDYDDDRRQ Epitope / Protein 97 106 When altered, amino acids shown in red lead to a decrease of IgE binding: PGDYDDDRRQ
6 PRREEGGRWG Epitope / Protein 107 116 When altered, amino acids shown in red lead to a decrease of IgE binding PRREEGGRWG
7 REREEDWRQP Epitope / Protein 123 132 When altered, amino acids shown in red lead to a decrease of IgE binding: REREEDWRQP
8 EDWRRPSHQQ Epitope / Protein 134 143 When altered, amino acids shown in red lead to a decrease of IgE binding: EDWRRPSHQQ
9 QPRKIRPEGR Epitope / Protein 143 152 When altered, amino acids shown in red lead to a decrease of IgE binding: QPRKIRPEGR
10 TPGQFEDFFP Epitope / Protein 294 303 When altered, amino acids shown in red lead to a decrease of IgE binding: TPGQFEDFFP
11 SYLQEFSRNT Epitope / Protein 311 320 When altered, amino acids shown in red lead to a decrease of IgE binding: SYLQEFSRNT Mutation: G315E
12 FNAEFNEIRR Epitope / Protein 325 334 When altered, amino acids shown in red lead to a decrease of IgE binding: FNAEFNEIRR
13 EQEERGQRRW Epitope / Protein 344 353 When altered, amino acids shown in red lead to a decrease of IgE binding: EQEERGQRRW
14 DITNPINLRE Epitope / Protein 393 402 When altered, amino acids shown in red lead to a decrease of IgE binding: DITNPINLRE
15 NNFGKLFEVK Epitope / Protein 409 418 When altered, amino acids shown in red lead to a decrease of IgE binding: NNFGKLFEVK
16 RRYTARLKEG Epitope / Protein 498 507 When altered, amino acids shown in red lead to a decrease of IgE binding: RRYTARLKEG
17 ELHLLGFGIN Epitope / Protein 525 534 When altered, amino acids shown in red lead to a decrease of IgE binding: ELHLLGFGIN
18 HRIFLAGDKD Epitope / Protein 539 548 When altered, amino acids shown in red lead to a decrease of IgE binding: HRIFLAGDKD
19 IDQIEKQAKD Epitope / Protein 551 560 When altered, amino acids shown in red lead to a decrease of IgE binding: IDQIEKQAKD
20 KDLAFPGSGE Epitope / Protein 559 568 When altered, amino acids shown in red lead to a decrease of IgE binding: KDLAFPGSGE
21 KESHFVSARP Epitope / Protein 578 587 When altered, amino acids shown in red lead to a decrease of IgE binding: KESHFVSARP

<Epitope Information (2)>

Pubmed 24365751
Uniprot Acc. P43237
Title IgE versus IgG4 epitopes of the peanut allergen Ara h 1 in patients with severe allergy.
Author Bogh KL, Nielsen H, Eiwegger T, Madsen CB, Mills EN, Rigby NM, Szepfalusi Z, Roggen EL.
Journal Mol Immunol. 2014 Apr;58(2):169-76. doi: 10.1016/j.molimm.2013.11.014. Epub 2013 Dec 22.
Method phage display
No. Epitope Sequences Blast Search Start End Description Type
1 - - -

<Epitope Information (3)>

Pubmed 32442779
Uniprot Acc. P43238
Title
Author
Journal
Method Peptide array
No. Epitope Sequences Blast Search Start End Description Type
1 AGGEQEERGQRRWST Epitope / Protein 341 355 Cupin 7S globulin(Arachis hypogaea)
2 ELVAVRKEQQQRGRR Epitope / Protein 466 480 Cupin 7S globulin(Arachis hypogaea)
3 RLQGRQQEQQFKREL Epitope / Protein 131 145 Conglutin-7 (Arachis hypogaea)
4 MRRRVEQEQEQEQDE Epitope / Protein 61 75 Conglutin (Arachis hypogaea)
5 MAEALYYGGRQRQEQ Epitope / Protein 1 15 oleosin (Arachis hypogaea)

<Sugar Information>

Uniprot Acc Start End Description
P43237 516 516 N-linked (GlcNAc...) asparagine. {ECO:0000269|PubMed:10998264}.
P43238 521 521 N-linked (GlcNAc...) asparagine. {ECO:0000269|PubMed:10998264}.