| Allergen-Scientific Name | Taxonomy Name | Genbank Common Name | Category |
|---|---|---|---|
| Jun a 1 | Juniperus ashei | Ozark white cedar |
|
| IsoAllergen | Source of Allergen Name |
|---|---|
IsoAllergen
|
ADFS |
| DataSource | UniProt Acc | Motif |
Original Reference (gi number) |
Allergen Description |
|---|---|---|---|---|
| P81294 | ADFS_0013 | 4138877 | Pectate lyase 1 , Major pollen allergen Jun a 1 , Allergen=Jun a 1 | |
| P81294 | ADFS_0013 | 4138877 | Pectate lyase 1 , Major pollen allergen Jun a 1 , Allergen=Jun a 1 | |
| P81294 | ADFS_0013 | 9087152 | Pectate lyase 1 , Major pollen allergen Jun a 1 , Allergen=Jun a 1 |
| Pubmed | 14563374 |
| Uniprot Acc. | P81294 |
| Title | Major linear IgE epitopes of mountain cedar pollen allergen Jun a 1 map to the pectate lyase catalytic site. |
| Author | Midoro-Horiuti T, Mathura V, Schein CH, Braun W, Yu S, Watanabe M, Lee JC, Brooks EG, Goldblum RM. |
| Journal | Mol Immunol. 2003 Dec;40(8):555-62. |
| Method | SPOT-method |
| No. | Epitope Sequences | Blast Search | Start | End | Description | Type |
|---|---|---|---|---|---|---|
| 1 | IFSQNMNIKLKMP | Epitope / Protein | 71 | 83 | ||
| 2 | AFNQFGPNAGQR | Epitope / Protein | 218 | 229 | ||
| 3 | MPRARYGL | Epitope / Protein | 230 | 237 | ||
| 4 | WRSTRDAFING | Epitope / Protein | 296 | 306 |
| Pubmed | 15975657 |
| Uniprot Acc. | P81294 |
| Title | Structural basis for epitope sharing between group 1 allergens of cedar pollen. |
| Author | Midoro-Horiuti T, Schein CH, Mathura V, Braun W, Czerwinski EW, Togawa A, Kondo Y, Oka T, Watanabe M, Goldblum RM. |
| Journal | Mol Immunol. 2006 Feb;43(6):509-18 |
| Method | SPOT-method |
| No. | Epitope Sequences | Blast Search | Start | End | Description | Type |
|---|---|---|---|---|---|---|
| 1 | IFSQNMNIKLKMP | Epitope / Protein | 92 | 104 | Cross-reactive to Japanese ceder (Cry j 1)-sensitive patients' IgE | |
| 2 | AFNQFGPNAGQR | Epitope / Protein | 239 | 250 | Cross-reactive to Japanese ceder (Cry j 1)-sensitive patients' IgE | |
| 3 | MPRARYGL | Epitope / Protein | 251 | 258 | ||
| 4 | WRSTRDAFINGAY | Epitope / Protein | 317 | 329 | Cross-reactive to Japanese ceder (Cry j 1)-sensitive patients' IgE |
| Pubmed | 16735798 |
| Uniprot Acc. | P81294 |
| Title | Lysine as a critical amino acid for IgE binding in Phl p 5b C terminus. |
| Author | Gehlhar K, Rajashankar KR, Hofmann E, Betzel C, Weber W, Werner S, Bufe A. |
| Journal | Int Arch Allergy Immunol. 2006;140(4):285-94. |
| Method | Site-directedmutagenesis & inhibition-ELISA |
| No. | Epitope Sequences | Blast Search | Start | End | Description | Type |
|---|---|---|---|---|---|---|
| 1 | K,K,K,K,K,K,K,K,K,K | Epitope / Protein | - | - | Ten potential IgE-interacting residues of Phl p 5b (K130, K141, K147, K171, K174, K185, K195, K219, and K229) were identified |